Tropical Journal of Pharmaceutical Research

Original Research Article | OPEN ACCESS

Relationship between traditional Chinese medicine constitution and pregnancy outcome in elderly primiparae

Junxin Qiu¹, Juan Zhao², Ping Feng², Huiqin Zhou², Hong Li²

¹Department of TCM Internal, Jinshan Hospital of Fudan University, Shanghai 201508, China; ²Department of Obstetrical, International Peace Maternity and Child Health Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200030, China.

For correspondence:- Hong Li Email: hong201112@gmail.com

Accepted: 29 June 2023 Published: 31 July 2023

Citation: Qiu J, Zhao J, Feng P, Zhou H, Li H. Relationship between traditional Chinese medicine constitution and pregnancy outcome in elderly primiparae. Trop J Pharm Res 2023; 22(7):1443-1449 doi: 10.4314/tjpr.v22i7.12

© 2023 The authors.
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Abstract

Purpose: To investigate the correlation between traditional Chinese medicine (TCM) constitution and pregnancy outcomes in elderly primiparae.

Methods: A cross-sectional case-control study was conducted on 113 elderly primiparae who were delivered in Jinshan Hospital of Fudan University, Shanghai, China from January 2019 to December 2019. The elderly primiparae was the study group. Using a random ratio of 1:3, 393 primiparous women of suitable age who were delivered in the hospital at the same period were selected as the control group. A traditional Chinese medicine (TCM) questionnaire was used to collect clinical data, and differences between the two groups were compared.

Results: The incidence of gestational diabetes mellitus was significantly higher in the study group (elderly primiparae) with phlegm dampness constitution and qi stagnation constitution than in control group (appropriate-age primiparae) (p < 0.05). The incidence of hypertension was significantly higher in the study group with yin deficiency constitution and special constitution than in control group (p < 0.05). The frequency of selective cesarean section in study group with a biased qi-deficiency constitution, yang-deficiency constitution, and yin-deficiency constitution were significantly higher than control group (p < 0.05).

Conclusion: There is a correlation between pregnancy outcomes in old age and TCM constitution. Individualized diet and exercise programs may be formulated in early pregnancy (based on the type of physique) to improve pregnancy outcomes in elderly primiparae.

Keywords: Elderly primiparae, TCM constitution, Pregnancy outcome